Aloes

Aloes posseses a chronic anti-inflammatory activity. It is useful for calming a wide variety of types of inflammation, and when ingested is a valuable source of interesting glyconutrients. Aloes is easy to take and relatively economical, and without many contra-indications or side effects. 

 

"Polymyositis is one of several autoimmune diseases that show the same profile - a lack of dietary sugars - the inability to absorb them - or abnormalities in their structures. For patients with polymyositis, glyconutrient supplementation, such as Ambrotose or other aloes concentrates, may provide benefits."(From Ambrotose company website) [1]

However, the company does not appear to have a very good reputation, and I can find no real studies that are independant that support the companies claims.

Aloe contains a complex combination of minerals, sugars, vitamins and enzymes, fatty acids and hormones. A more detailed breakdown can be found here. (Joseph, Raj. October 2010) [2]

Huge article of aloes chemistry here. (Chow, Williamson, Yates, Goux) [3]

A patent has been taken on the use of Aloes preparation acemann for use in treatment of inflammatory diseases. According to the patent Acemannan has now been discovered to be a potent inducer of Interleukin 1 (Il-1) and prostaglandin E2 (PGE2) production by human peripheral blood adherent cells in culture. Il-1 has been shown to be an important macrophage product and is associated with influencing the activity and product production of T lymphocytes, fibroblasts, B lymphocytes and endothelial cells. Acemannan has no demonstrated toxicity, and acts as an adjuvant and immunoenhancer. Interestingly, the patent cites many studies showing Aloe vera and various of its components to be potent anti-inflammatories. (McAnalley, Carpenter, McDaniel. June 1995) [4]

Aloes as anti-oxidant and free radical scavenger, also anti-inflammatory (Harlev, Nevo, Lansky, Ofir, Bishayee. April 2012) [5]

"Aloes posseses chronic anti-inflammatory activity". (Sarkar, Dutta, Das, Sarkar, Mandal, Chatterjee. 2005) [6]

"One interesting substance that has been isolated from aloes is an anti-inflammatory know as c-glucosyl chromone" (Surjushe, Vasani, Saple. 2008) [7]

 

 

 

Found at Ambrotose company website. Glyconutrients - Ambrotose,.

Baby J, Raj J. PHARMACOGNOSTIC AND PHYTOCHEMICAL PROPERTIES OF ALOE VERA LINN - AN OVERVIEW. Interdisciplinary Research Unit, Dept. of Biotechnology, Malankara Catholic College. 2010 Oct. as found at http://globalresearchonline.net

Chow J, Williamson D, Kenneth M, Yates K, et al. Chemical Characterization of the Immunomodulating Polysaccharide of Aloe Vera L. Department of Chemistry, University of Texas. as found at www.iasc.org/AloeStructure080604.pdf

McAnalley B, Carpenter R, McDaniel H. Uses of aloe products in the treatment of inflammatory diseases. 1995 June. as found at US Patent Number 5587364

Harlev E, Nevo E, Lansky E, et al. Anticancer Potential of Aloes: Antioxidant, Antiproliferative, and Immunostimulatory Attributes. Institute of Evolution and International Graduate Center of Evolution, University of Haifa, Mount Carmel, Haifa, Israel; Thieme's Online Journal Services. Apr. 19, 2012 as found at Thieme Plant Medica

Sarkar D, Dutta A, Das M, et al. Effect of Aloe vera on nitric oxide production by macrophages during inflammation. Indian J Pharmacol 2005;37:371-5 as found at http://www.ijp-online.com/text.asp?2005/37/6/371/19073

Surjushe A, Vasani R, Saple D. ALOE VERA: A SHORT REVIEW. Indian J Dermatol. 2008. as found at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763764/